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Drug considered as the drug of choice in a specific asthma emergency treatment include:
Correct statements regarding Erythromycin ESTOLATE may include:
I- Primarily effective against gram-positive bacteria and also have activity against some Gram-negative bacteria
II- It is a macro lid antibiotic very useful as alternative to penicillin for those that have Allergy to penicillin antibiotics
III- Regular erythromycin is better absorbed from GIT that erythromycin estolate
All of the following are examples of DMRA-Disease Modifying Antirheumatic Agents, EXCEPT
All are correct concerning the action of corticosteroids in asthma status, EXCEPT:
Which of the following conditions are quinolone antimicrobial drugs mainly used?
Cigarette smoke causes an increase in levels of CYP1A isozymes. Theophylline is primarily metabolized by the CYP1A system. What would happen to theophylline clearance for an asthmatic patient in hospital who could not smoke?
Examples of drug(s) that may precipitate asthma include all of the following, EXCEPT:
Which of the following is not directly related to a drug toxicity of Ibuprofen?
Autoimmune disorders include which of the following?
I Graves' disease
II Systemic Lupus Erythematosus
III Osteoarthritis
If the total body clearance of a drug is 200 mL/min in a normal healthy adult and the renal clearance is 10 mL/min then one may assume that:
Osteoporosis is a disease characterized by loss of bone mass and may be aggravated by:
I-Corticosteroids
II-Menopausa
III-Grave’s disease
Mercapturic acid derivatives in phase II metabolism can result from reactions of:
The style of management in which the owner of a pharmacy emphasizes the development of detailed policies and written procedures for employees to observe at all times is referred to as:
Importance of Vitamin D in osteoporosis:
I- Increase the absorption of calcium from the small intestine
II- The best vitamin D analog to treat osteoporosis is calcitriol
III- Antacids containing aluminum and magnesium may interfere with proper activity of vitamin D.
Aerosol OT (AOT) is used in veterinary medicine as a laxative. If 250 g of AOT is dissolved in 1 000 mL of glycerin (density of glycerin is 1.25 g/mL), the concentration of AOT in the solution is:
The pharmacist fills a prescription for sumatriptan 100 mg tablets for a migraine patient. Appropriate information to provide to the patient includes which of the following?
A patients with allergy to Sulphonamides (i.e.: SulphametoxazolE. can take all of the following medications, EXCEPT:
Structure-activity studies of cholinergic drugs indicate that:
I maximum activity is achieved when the quaternary nitrogen is three carbons removed from the ester oxo group.
II structures which display a quasi-ring conformation exhibit muscarinic activity.
III one methyl group of the trimethylammonium group can be replaced by an ethyl group with only slight loss of activity.
True statements regarding the use of monoclonal antibodies include which of the following?
I Flu-like symptoms commonly occur at the start of therapy.
II T cells are blocked from initiating the rejection process.
III Orthoclone is a human immunoglobulin product.
Drugs shown to be effective in the prevention of Travellers'
Diarrhea, which might have been prescribed for SM include:
I doxycycline
II cotrimoxazole
III amoxicillin
A patient purchasing sublingual nitroglycerin tablets should be told to store the medication:
Potassium-sparing diuretics:
I exert their effect in the proximal tubule.
II may cause intracellular alkalosis.
III include the aldosterone antagonists.
Diazepam Injection U.S.P
Diazepam 5 mg/ml
Ethanol 10%
Propylene glycol 40%
Benzyl alcohol 1.5%
Water for Injection qs 100%
In the formulation given above, the following ingredient(s) function(s) as a cosolvent(s):
I ethanol
II propylene glycol
III benzyl alcohol
Which of the following is not directly related to a drug toxicity of Nitroglycerin?
How much of a 10 mg dose of morphine reaches the systemic circulation given F = .24?
Which of the following statements best describes the action of the antitubercular agent ISONIAZID?
Correct statements regarding aminoglycosides may include:
I- Has a half-life of 12hours
II- The effect continue remain after all drug is eliminated
III- The relation plasma concentration and half-life is not clear
Example of drug(s) used in treatment of tuberculosis include:
I- Isoniazid
II- Rifampin
III- Ethambutol
Resistance is the major problem with penicillins due to ability of bacteria to breakdown the lactam ring of penicillin and inactivates the drug. To overcome these problem penicillins can be administrated together with β-lactamase inhibitors.
Examples of β-lactamase inhibitors is/are:
I- Clavulanic acid
II- Sulbactam
III- Tazobactam
Which of the following agents would be used in the treatment of infections caused by Helicobacter pylori as combination therapy?
Which of the following is an anti-infective agent with lowest therapeutic index?
Correct statements regarding Pellagra include:
I- Caused due to deficiency of niacin
II- Caused by failure in converting tryptophan to niacin
III- Characterized by dermatitis, diarrhea and dementia
Antioxidants, which mechanistically act as reducing agents, include:
I ascorbic acid
II sodium bisulfite
III citric acid
All of the following statements are true regarding chronic inflammation, EXCEPT:
The codon sequence Adenine-Guanine-Cytosine-Uracil is seen in
I- RNAs
II- DNAs
III- Both DNAs and RNAs
Which of the following statements is/are correct regarding enzymes?
I-Enzymes are proteins
II- Enzymes are catalyst because they are never altered during a reaction
III- Michaelis-Menten theory describe the enzymatic reactions
Vitamin that requires an intrinsic factor to be carried out to ileum in order to suffer absorption from the small intestine:
Both isoxazole and oxazole rings are found as substituents in some bacteriostatic sulfanilamides. They are present in these structures specifically because of their:
If the pKa of phenobarbital is 7.4, what approximate fraction of the drug would be ionized at pH 8.4?
Gamma aminobutyric acid (GABA. is:
I the major inhibitory neurotransmitter in the brain
II found primarily in interneurons
III synthesized from glycine
Atropine is the primary example of an important class of muscarinic antagonists which are esters of tropic acid and which contain:
Common etiologic agents of community-acquired pneumonia include:
I Escherichia coli
II Haemophilus influenzae
III Mycoplasma pneumoniae
Allopurinol, xanthine oxidase inhibitor, used in gout treatment may produce all the following side effects, EXCEPT:
All of the following drugs will increase the heart rate directly or by reflex when injected intravenously into a young healthy adult, EXCEPT:
An angiotensin-converting enzyme (ACE. inhibitor for which both renal elimination and metabolism are important in the elimination of the drug and its active metabolites is:
When evaluating patients with angina for possible development of nitrate tolerance, true statements include:
I tolerance is rarely associated with isosorbide dinitrate.
II tolerance does not occur in patients who are concurrently on
metoprolol.
III tolerance is dependent upon the administration schedule of nitrate medication.
Goals of gout treatment may include:
I- Reduce inflammation during acute attacks
II- Accelerate renal excretion of uric acid
III- Reduce the conversion of purine to uric acid
In an adequately powered, randomized controlled trial conducted over 2 years, the desired clinical outcome (i.e. prevention of a serious cardiovascular event) with a new drug is achieved in 25% of the study sample. In the patients who receive a placebo, only 15% obtain the same clinical benefit. The relative risk reduction achieved with the new drug over the study period is:
TESTED 23 Nov 2024